Serie A Big 5: Who has the toughest start in 2025-26? | OneFootball

Milan probably have the toughest start to the season among the big five, facing Bologna, Napoli, Juventus, Fiorentina, Atalanta and Roma in the first ten games.

The Serie A fixture list for the 2025-26 campaign was released on Friday.

Football Italia has put down the opening ten games for the big five teams in Italy: Napoli, Inter, Juventus, Roma and Milan and the Rossoneri seem to have the toughest fixture list.

Milan have toughest Serie A start in 2025-26

Juventus coach Massimiliano Allegri (Photo by Marco BERTORELLO / AFP) (Photo by MARCO BERTORELLO/AFP via Getty Images)

Massimiliano Allegri’s men, in fact, will meet many of their direct rivals in the opening ten games, and the Derby della Madonnina against Inter will come shortly afterwards in Round 12.

Roma haven’t been quite lucky with the draw either, making their debut against Bologna at home, meeting city rivals Lazio in Round 4 and then Fiorentina, Inter and Milan.

Soft Napoli start in 2025-26 Serie A

NAPLES, ITALY – MAY 23: Antonio Conte, Head Coach of Napoli, kisses the Serie A TIM Scudetto title trophy after his team’s victory in the Serie A match between Napoli and Cagliari at Stadio Diego Armando Maradona on May 23, 2025 in Naples, Italy. (Photo by Francesco Pecoraro/Getty Images)

Defending champions Napoli will face both Milanese sides in the opening ten rounds, as well as Fiorentina away, but they will also encounter two newly promoted teams, Sassuolo and Pisa.

Inter have big games against Juventus, Roma and Napoli as well as Fiorentina, but also matches against Cremonese and Sassuolo coming from Serie B.

Juventus host Atalanta and Milan in consecutive matches in Rounds five and six, but the first big game for them is in Round 3 against Inter, also at the Allianz Stadium.

Napoli **

Sassuolo-Napoli Napoli-Cagliari Fiorentina-Napoli Napoli-Pisa Milan-Napoli Napoli-Genoa Torino-Napoli Napoli-Inter Lecce-Napoli Napoli-Como

Inter ***

Inter vs Torino Inter vs Udinese Juventus vs Inter Inter vs Sassuolo Cagliari vs Inter Inter vs Cremonese Roma vs Inter Napoli vs Inter Inter vs Fiorentina Verona vs Inter

Juventus ***

Juventus-Parma Genoa-Juventus Juventus-Inter Verona-Juventus Juventus-Atalanta Juventus-Milan  Como-Juventus Lazio-Juventus Juventus-Udinese Cremonese-Juventus

Roma ****

Roma-Bologna Pisa-Roma Roma-Torino Lazio-Roma Roma-Verona Fiorentina-Roma Roma-Inter Sassuolo-Roma Roma-Parma Milan-Roma

Milan *****

Milan-Cremonese Lecce-Milan Milan-Bologna Udinese-Milan Milan-Napoli Juventus-Milan Milan-Fiorentina Milan-Pisa Atalanta-Milan Milan-Roma

difficulty level from * to *****