Serie A 2025-26: Matchday 1 Fixtures & Season Preview | OneFootball

With the start of the 2025-25 Serie A season just under one month away, anticipation is mounting amongst fans of the Italian top flight.

Napoli head into the upcoming campaign as the bookmakers’ favourites to retain the title, but several clubs have a genuine chance of toppling them.

With that in mind, read on as we look at the latest outright odds and Matchday 1 fixtures, before taking a closer look at the Serie A title race.

NAPLES, ITALY – MAY 26: SSC Napoli players and staff on two busses celebrate the victory of Serie A TIM during the SSC Napoli Trophy Parade on May 26, 2025 in Naples, Italy. (Photo by Francesco Pecoraro/Getty Images)

Serie A 2025/26: Matchday 1 Fixtures

Saturday, August 23

Sunday, August 24

Monday, August 25

Serie A 2025-26: Season Preview

Antonio Conte did a superb job in his first season as Napoli manager and will fancy his chances of guiding them to another Scudetto this term.

The board have backed Conte in the summer transfer window, bringing in several new players to strengthen an already impressive squad.

Centre-back Sam Beukema is a shrewd acquisition from Bologna, while Noa Lang will add attacking thrust after joining from PSV Eindhoven.

However, the club’s standout signing could be Kevin De Bruyne, who has arrived on a free transfer after a trophy-laden spell with Manchester City.

Napoli will be tough to stop in their quest to retain the Serie A title, but last season’s runners-up Inter could give them a run for their money.

Cristian Chivu has replaced Simone Inzaghi as manager, and he will be eager to build on the solid foundations he left behind.

CHARLOTTE, NORTH CAROLINA – JUNE 30: Cristian Chivu, Head Coach of FC Internazionale Milano, looks on during the FIFA Club World Cup 2025 round of 16 match between FC Internazionale Milano and Fluminense FC at Bank of America Stadium on June 30, 2025 in Charlotte, North Carolina. (Photo by Michael Reaves/Getty Images)

Chivu guided Parma to safety in his first managerial role last season, but could not resist the temptation to return to a club he represented with distinction as a player.

Inter have been active during the transfer window, and more new arrivals are expected at the San Siro before the deadline. They should challenge this season.

Juventus are also expected to be in the mix. Manager Igor Tudor guided them to Champions League qualification after replacing Thiago Motta in March and will be keen to make further progress.

The Turin giants have signed several talented players this summer, including Jonathan David, who has joined the club on a free transfer from Ligue 1 outfit Lille.

Jonathan David signs his Juventus contract

David bagged 146 goals and 45 assists in 315 appearances for the French club and could be a prime candidate to win the Golden Boot in Serie A this season.

Roma, Milan, Atalanta and Lazio will be in contention for European qualification, but none of them appeals as likely winners of the title.

Juventus, Napoli and Inter are fancied to fill the top three positions, although there will probably be little to choose between them at the end of the campaign.

Serie A 2025-26: Outright Odds

Reigning Serie A champions Napoli head the outright market this season and will likely be a popular pick for many sports bettors.

Fans inclined towards betting can make use of the bet365 bonus code if they fancy wagering on the title race. Here are the outright odds: