Lyon vs Manchester United - Preview, prediction, team news and lineups | OneFootball

Manchester United have drawn both previous visits to Lyon, 2-2 at Stade de Gerland in 2004 and 1-1 four years later.

Olympique Lyonnais have won only one of their last ten home games against English opposition; Man United have won each of their last three trips to France, unbeaten in six on French soil.

Olympique Lyonnais vs Manchester United Preview

It's been an undeniably dismal seasons for Manchester United, but they can still salvage the campaign with Europa League glory, and this trip to Southern France is their next hurdle. The Red Devils are still unbeaten in this season's competition, concluding the league phase with five straight wins, before overcoming Real Sociedad in the round of 16. After a 1-1 draw in San Sebastián, Bruno Fernandes' hat-trick back at Old Trafford secured their passage into the last eight. Man United have now reached, at least, the quarter-finals each of the last five times they've featured in the Europa League, hoisting the trophy aloft in 2017, before being beaten finalists four years later.

Right now, Rúben Amorim's team are down in 13th in the Premier League, following Sunday's goalless draw with Manchester City, branded the worst derby of all-time. Thus, the Red Devils are firmly all-in on the Europa League, so can they claim a positive first leg result in Décines-Charpieu?

As for Olympique Lyonnais, they're aiming to reach just a fifth major European semi-final, yet to capture silverware on the continent. Les Gones finished sixth in the league phase, two points below their opponents, their sole defeat coming when Beşiktaş visited France in October. Then, in the last 16, Lyon demolished Steaua București 7-1 on aggregate, departing Arena Națională 3-1 winners, before Georges Mikautadze and Ernest Nuamah both bagged braces back at home.

Meanwhile, domestically, OL fought back from a goal down to beat Lille 2-1 on Saturday night, so remain fifth in Ligue 1, a point adrift Strasbourg, the current tenants of the final Champions League position. Lyon have lost each of their last three two-legged ties against Premier League opposition, their most-recent continental escapade ended by West Ham three seasons ago. Thus, if Paulo Fonseca's side are going to cause an upset, this first leg at Parc Olympique Lyonnais feels must win.

Olympique Lyonnais vs Manchester United Head-to-Head Record

Olympique Lyonnais Team News

Manager Paulo Fonseca is currently serving a nine-month touchline ban in Ligue 1, after head-butting referee Benoît Millot, but this does not apply to UEFA competition.

On the pitch, the biggest decision he has to make comes in attack. Georges Mikautadze is set to lead the line, chosen over Alexandre Lacazette who, after scoring on Saturday, need 27 more goals to become Lyon's all-time record-scorer; Fleury Di Nallo has held this record since 1974.

Elsewhere, Malick Fofana and Ernest Nuamah are injured, while Nemanja Matić will start against his former club at the base of midfield. Ainsley Maitland-Niles, Moussa Niakhaté, Corentin Tolisso and the aforementioned Lacazette would sit out the clash at Old Trafford if cautioned.

Olympique Lyonnais predicted lineup vs Manchester United: (4-2-3-1): Perri; Maitland-Niles, Mata, Niakhaté, Tagliafico; Tessmann, Matić, Cherki, Tolisso, Almada; Mikautadze,

Olympique Lyonnais Player to Watch vs Manchester United

Georges Mikautadze, joint-golden boot winner at last summer's Euros, has scored 14 goals since joining home town club Lyon last summer, four of which have come in the Europa League.

Manchester United Team News

Lisandro Martínez, Jonny Evans, Ayden Heaven, Kobbie Mainoo and Amad remain sidelined long-term, but Rúben Amorim does now have a few options from which to choose. Matthijs de Ligt missed the Manchester derby due to a knock, but is expected to be fit for this one, potentially getting the nod over Harry Maguire.

Meantime, Mason Mount has come off the bench during the last two fixtures, having not featured since the famous derby won of 15 December beforehand, while Luke Shaw was an unused substitute on Sunday; he last took to the field on 1 December.

Chido Obi-Martin cannot feature, as he isn't in the UEFA squad, so Joshua Zirkzee, scorer in San Sebastián, could start in place of Rasmus Højlund in attack. Casemiro and de Ligt are walking the yellow card tightrope.

Manchester United predicted lineup vs Olympique Lyonnais: (3-4-3): Onana; Yoro, de Ligt, Mazraoui; Dalot, Ugarte, Casemiro, Dorgu; Garnacho, Fernandes, Zirkzee.

Manchester United Player to Watch vs Olympique Lyonnais

Bruno Fernandes has 16 goals to his name this season, while his hat-trick against Real Sociedad further improved his Europa League ratio which now stands at 24 goals in 53 appearances.

Olympique Lyonnais vs Manchester United Prediction

Goals are guaranteed and we are backing Lyon for a narrow first leg victory in France, which would set up the second leg at Old Trafford perfectly: Olympique Lyonnais 2-1 Manchester United.

Olympique Lyonnais vs Manchester United FAQs - Europa League

How to watch Olympique Lyonnais vs Manchester United Europa League game on TV channel?

Olympique Lyonnais vs Manchester United Europa League game will be available on the following TV channels;

How to watch Olympique Lyonnais vs Manchester United Europa League game on live streaming?

Olympique Lyonnais vs Manchester United Europa League game will be available on the following streaming services;

What is the date and kick-off time for Olympique Lyonnais vs Manchester United in the Europa League?

Olympique Lyonnais vs Manchester United takes place on Thursday 10 April 2025, with kick off at 20:00 (BST), 15:00 (EDT) & 12:00 (PDT).